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Use your knowledge of the Heck reaction to suggest a structure for compound (12). Using curly arrow notation, suggest a plausible mechanism the reaction. n

  1.  Use your knowledge of the Heck reaction to suggest a structure for compound (12). 
  2.  Using curly arrow notation, suggest a plausible mechanism the reaction.
  3. n

Br NC CO,H.CY2NH H Pd(OAc)2, LiCI, LIOAC, Et,N (10) NC. compound (12) hepatitis C polymerase inhibitor (13) (11)

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