Question
USING R (r studio) You are studying a rare genetic disease caused by a mutation in a particular gene. You have collected data from 100
USING R (r studio)
You are studying a rare genetic disease caused by a mutation in a particular gene. You have collected data from 100 individuals, 50 of whom have the disease (cases) and 50 of whom do not (controls). You have also genotyped the individuals for the mutation, and you find that 10 cases and 1 control have the mutation.
Build a contingency table for this data and demonstrate how an odds ratio can be calculated from first principles and explain the association shown. Then perform Fisher's exact test to determine whether the observed association between the mutation and the disease is statistically significant. Provide a full commentary on the analysis, breaking down the code used and explain what the p-value and odds ratio show
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