Using the data below, suppose we focus on the proportions of patients who show improvement. Is there a statistically significant difference in the proportions of patients who show improvement between treatments 1 and 2. Run the test at a 5% level of significance.

Symptoms Worsened No Effect Symptoms Improved Total

Treatment 1 22 14 14 50

Treatment 2 14 15 21 50

Treatment 3 9 12 29 50

Please provide answer and explanation.