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We are conducting a study to determine the effects of drug on hypertension. The arterial blood pressure of a random sample of 12 patients is

We are conducting a study to determine the effects of drug on hypertension. The arterial blood pressure of a random sample of 12 patients is measured before and after the treatment, the data are showing below:

Patient ID Before After
1 140 90
2 120 110
3 120 80
4 105 100
5 100 100
6 120 123
7 160 144
8 111 84
9 98 94
10 90 90
11 102 104
12 98 98

Please conduct a sign test to find out whether the surgery changed the arterial blood pressure.

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