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What are the molecular pathways involved in immunological tolerance, including central and peripheral mechanisms that prevent self-reactive lymphocytes from causing autoimmune reactions, and how do

What are the molecular pathways involved in immunological tolerance, including central and peripheral mechanisms that prevent self-reactive lymphocytes from causing autoimmune reactions, and how do dysregulations in tolerance mechanisms contribute to autoimmune diseases ?

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Immunological tolerance refers to the bodys ability to distinguish self from nonself and to prevent the immune system from attacking its own tissues This is crucial for maintaining immune homeostasis ... blur-text-image

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