What best describes the different formulations of 5-aminosalicylates (5-ASA)? The different formulations change the length of time 5-ASA stays in the bowel. The different formulations are recognized to be less effective compared to the original product. The different formulations are still being developed and are not available for use. The different formulations are administered in distinct ways and target different segments of the bowel. The different formulations must be taken as suppositories only