1. What is the statistical definition of "confounding"?
2. What are the 2 primary sources of confounding discussed in the assigned reading? (Beyond the numbers) Ch 1-3
3. What is a response variable? Give an example not the placebo effect
4. What is an explanatory variable? Give an example not the placebo effect
5. Describe a simple experiment that measures one variable's effect on another. Name at least 1 potential confounding variable.
6. How did an understanding of the placebo effect change arthroscopic knee surgery?
7. When done correctly, explain how comparison addresses confounding
8. Suppose a social experiment is being done to compare two ways that a police officer can handle a domestic violence call. Effectiveness is measured by the number of call-backs to that address within a week. How might the treatment randomization be handles here?
9. What critical mistake did the manufacturer's or ribavirin make in their early drug studies?
10. What percentage of all patients studied in the ribavirin trial developed AIDS?
11. What were the treatments in the fibanserin study?
12. What percent increase from baseline in the number of sexually satisfying events was reported by women in the placebo group?
13. What is the definition of "statistical significance?"
14. Were the fibanserin results statistically signigicant?
15. Why didn't the FDA approve fibanserin?