What would be the total surface area (in m2) of the ion exchange resin in problem 1 if a 2.50 L packed column (total volume) was used for purification?

1. Ion exchange resin is commonly used for purification of pharmaceutical products from a cell lysate (liquid solution). The surface area is an important consideration as it reflects the amount of product that can be adsorbed to the resin. A packed bed of spherical resin particles (see figure below) has a bulk density of 0.650g/cm3 and a density of 1.12g/cm3. Calculate the specific surface area of a resin particle (in m2/m3 ), porosity of the packed bed, and the specific surface area of the packed bed ( in m2/m3 )