When a drug with one ionization center (which is characterized by its pKa) is dissolved in a buffer solution (which is characterized by its pH), the relative concentration of its basic and acidic form can be calculated by the Henderson–Hasselbalch equation:

In the conditions as shown in the following table, please fill the blank cell with ionized, 50% ionized, neutral or 50% neutral according to the Henderson–Hasselbalch equation. (5 points)

Drug	pKa < pH - 2	pKa = pH - 2	pKa = pH	pKa = pH + 2	pKa > pH + 2
Acidic
Basic