Which of the following are weaknesses/limitations of birth cohort studies to evaluate the role of exposures across the life course on chronic disease risk? (select one best answer)

A. Reporting bias is minimal

B. Self-selection bias

C. Loss to follow-up bias

D. Information bias is minimal

E. The temporal relationship between exposure and outcome is not maintained (you cannot be certain that exposure happened before disease occurred).

F. B and C

G. A, D and E