With any QTL used in a selection program, it is always a good idea to

Question options:

	1) Verify the marker allele - QTL allele linkage phase regularly over time.
	2) Don't worry about the marker allele - QTL allele linkage phase over time because we cannot control recombination.
	3) Assume the marker allele - QTL allele linkage phase is maintained over time.

Q. Molecular and quantitative geneticists often use panels of markers to hunt for QTL so they can cover a wide area of the genome. Typically those analyses will be broken down to a chromosome by chromosome search for QTL, looking at all of the markers on a chromosome as an experimental unit. When multiple single nucleotide polymorphism (SNP) markers are available, it is better to

Question options:

	1) Group markers into a haploid genotype based on parental inheritance and analyze the group of markers as a virtual single marker looking for an association with a QTL.
	2) Analyze individual markers looking for associations with QTL for each marker accounting for their linkage distances.
	3) Analyze individual markers looking for associations with QTL for each marker and repeat the analysis as many times as there are markers on a chromosome.

Q. All of the various methods of detecting QTL have one common aspect. Assuming a generic marker locus M with alleles M and m, which of the following is the most correct...

Question options:

	1) All the methods are looking for a difference in phenotype between the individuals with an MM genotype versus an mm genotype.
	2) All the methods are looking for a phenotypic difference in the heterozygotes resulting from matings between individuals with an MM genotype and individuals with an mm genotype.
	3) All the methods are looking for a difference in selection response between the individuals with an MM genotype when they are selected as parents and mated versus when mm individuals are mated.

Q. QTL detection and using QTL in marker assisted selection of livestock and companion animals or fine mapping of genes and eventually gene therapy or genetic counseling in humans is the state of the art in Quantitative Genetics research. This makes QTL detection as a field of research a . . .

Question options:

	1) very dynamic area because allele frequencies can be dramatically altered which creates a need for a constant supply of new markers and new QTL.
	2) very static area because once QTL are found all of the molecular genetic mechanisms are known and allele frequencies can be dramatically altered by rapid selection response quickly eliminating "bad" alleles and solving a genetic problem.