Question
You are process manager at a small biologics company, responsible for providing purified proteins to clients e.g. for antibody generation. Your technical team has optimised
You are process manager at a small biologics company, responsible for providing purified proteins to clients e.g. for antibody generation. Your technical team has optimised protocols for batch production of a novel polypeptide (PX165) in both yeast and mammalian (CHO) cells.
Calculate the production costs per batch and fill in the Table below
Batch process time Media, Consumables, Energy Technical Labour (1 day = 8 hour shift) Level 3 tech (28.70/hr) Level 2 tech (18.60/hr) TOTAL COST per batch Yield of PX165 per batch Cost per mg of product (from a single batch) CHO cells 5 days 192.50 per day 3 hrs/day Level 3 tech 18.5mg Totals Yeast cells 3.5 days 158.40 per day 3.5hrs/day Level 2 tech 9.6mg Totals
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CHO Cells Labor Costs Level 3 tech 3 hrsday 2870hr 8610day Level 2 tech 0 hrsday 1860hr 0day ...
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Auditing Cases An Interactive Learning Approach
Authors: Mark S Beasley, Frank A. Buckless, Steven M. Glover, Douglas F Prawitt
7th Edition
0134421825, 9780134421827
