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You have been asked to evaluate the suitability of a second-hand fermenter for scaling up production of an aerobic culture at your employer's bioprocessing facility.

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You have been asked to evaluate the suitability of a second-hand fermenter for scaling up production of an aerobic culture at your employer's bioprocessing facility. Details of the existing (500L) fermenter, optimum production conditions and physical properties of the liquid phase are given in Table Q3.1. The specifications of the second-hand fermenter are given in Table Q3.2 (a) Show that the second-hand vessel has a standard Rushton geometry. [2 Marks] The liquid film mass transfer coefficient (kL) can be predicted using a bespoke design correlation developed by your company: kLa=0.013(VPg)0.4vs0.5 where kLa is the volumetric mass transfer coefficient (s1),Pg/V is the gassed power per unit volume of liquid (Wm3) and vs is the superficial gas velocity ( m min1). The correlation has the following limitations: 2L

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