Your friend studying computer science is designing a new protein folding tool that will predict protein folding pathways. Explain to them, using your UNISA BCH3703 module content, why a particular protein folds very rapidly in the presence of protein disulphide isomerase but aggregates and never folds correctly without protein disulphide isomerase. Also, the folding of the protein is very slow without peptidyl prolyl cis-trans isomerase enzymes.