A rotor-stator cell disruptor consists of a tapered cavity (stator) and a cone-shaped rotating rotor. The cell suspension is pumped through the very small gap between the rotor and stator, thus being disrupted by the high shear rate. It was found that at a residence time of 10 s, an intracellular antibiotic release was 2.65 mg/mL, and at a residence time of 30 s, it was 4.77 mg/ mL. If the residence time is increased to 60 s (by slowing the feed rate), what concentration of antibiotic is predicted? What is the percent extraction?