16. Healthy Teeth II In an experiment to study an oral rinse designed to prevent plaque buildup, subjects were divided into two groups: One group used a rinse with an antiplaque ingredient, and the control group used a rinse containing inactive ingredients. Suppose that the plaque growth on each person’s teeth was measured after using the rinse after 4 hours and then again after 8 hours. If you wish to estimate the difference in plaque growth from 4 to 8 hours, should you use a confidence interval based on a paired or an unpaired analysis? Explain.