Question: When RNA polymerase transcribes DNA, only one of the two DNA strands is used as a template. Referring to Figure 12.4, explain how RNA polymerase

When RNA polymerase transcribes DNA, only one of the two DNA strands is used as a template. Referring to Figure 12.4, explain how RNA polymerase determines which DNA strand is the template strand.

Figure 12.4

Coding strand Promoter -35 sequence 16-18 bp -10 sequence 5 TTGA AACTGT

Coding strand Promoter -35 sequence 16-18 bp -10 sequence 5 TTGA AACTGT GAA T T A A A ATAT 33 Template strand Transcriptional start site 3' A 5' 5 3' RNA A Transcription

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