(a) Write a mechanism for the esterification of propanoic acid with 18 O-labeled ethanol. Show clearly the...

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(a) Write a mechanism for the esterification of propanoic acid with ¹⁸O-labeled ethanol. Show clearly the fate of the ¹⁸O label.

(b) Acid-catalyzed hydrolysis of an unlabeled ester with ¹⁸O-labeled water (H₂ ¹⁸O) leads to incorporation of some ¹⁸O into both oxygens of the carboxylic acid product. Explain by a mechanism.

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Organic Chemistry structure and function

ISBN: 978-1429204941

6th edition

Authors: K. Peter C. Vollhardt, Neil E. Schore

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Question Posted: May 08, 2020 03:39 AM

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(a) Write a mechanism for the esterification of propanoic acid with 18 O-labeled ethanol. Show clearly the...

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a Esterification of Proponoic acid with CH08 H CH CH 0H COH CH CH C CH CH 80 o CH CH C C...View the full answer

Organic Chemistry structure and function

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