The following ketones cannot be synthesized by the acetoacetic ester method (why?), but they can be prepared by a modified version of it. The modification includes the preparation (by Claisen condensation) and use of an appropriate 3-ketoester, , containing an R group that appears in the final product. Synthesize each of the following ketones. For each, show the structure and synthesis of the necessary 3-ketoester as well.

(a)

(b)

(c)

(d)

Transcribed Image Text:

RCCH;COCH,CH3,