G protein-coupled receptors (GPCR) consist of seven transmembrane receptors consisting of alpha helices. The amino end of

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G protein-coupled receptors (GPCR) consist of seven transmembrane receptors consisting of alpha helices. The amino end of the protein is on the outside of the plasma membrane. The seven receptors are coupled either on the outside or inside of the plasma membrane. The helix between the 5th and 6th receptors is usually significantly longer than the other helices. A scientist wants to perform an experiment to inhibit the GPCR's function. Which of the following would the scientist aim to target?

(A) The phospholipid bilayer of the plasma membrane

(B) The external side of the receptor

(C) The internal side of the receptor

(D) The sequence of amino acids that make up the binding site for the G protein

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