Consider a time reversible continuous-time Markov chain having infinitesimal transition rates qi j and limiting probabilities {Pi}.

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Consider a time reversible continuous-time Markov chain having infinitesimal transition rates qi j and limiting probabilities {Pi}. Let A denote a set of states for this chain, and consider a new continuous-time Markov chain with transition rates q∗

i j given by q∗

i j =



cqi j, if i ∈ A, j ∈/ A qi j, otherwise?

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