Question: The unfolding, or denaturation, of a biological macromolecule may be brought about by treatment with substances, called denaturants that disrupt the intermolecular interactions responsible for

The unfolding, or denaturation, of a biological macromolecule may be brought about by treatment with substances, called denaturants that disrupt the intermolecular interactions responsible for the native three-dimensional conformation of the polymer. For example, urea, CO (NH2)2' competes for NH and CO groups and interferes with hydrogen bonding in a polypeptide.

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