Although the synthesis of heterocyclic rings was not discussed in the text, many such syntheses employ reactions that are similar or identical to reactions in other parts of the text. Give curved-arrow mechanisms for the reactions involved in each of the heterocyclic syntheses in Fig. P25.47 on p. 1264. Begin, as always, by analyzing the relationship between the atoms in the reactants and products.
Fig. P25.47
(a) Hinsberg thiophene synthesis:

(b) combes quinoline synthesis:

Transcribed Image Text:

Ph Ph I NaOMe, MeOH 2) H2O, heat 3) HCI MeO.C CH H0t