Antibodies raised against a macromolecular antigen usually produce an antigen-antibody precipitate when mixed with that antigen. Explain

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Antibodies raised against a macromolecular antigen usually produce an antigen-antibody precipitate when mixed with that antigen. Explain why no precipitate forms when
(a) Fab fragments from those antibodies are mixed with the antigen;
(b) Antibodies raised against a small antigen are mixed with that small antigen; and
(c) The antibody is in great excess over the antigen and vice versa.
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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