Apart from genome size, what factors make complete assembly of a eukaryotic genome more difficult than assembly

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Apart from genome size, what factors make complete assembly of a eukaryotic genome more difficult than assembly of a prokaryotic genome?
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Brock Biology of Microorganisms

ISBN: 978-0321897398

14th edition

Authors: Michael Madigan, John Martinko, Kelly Bender, Daniel Buckley

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