As described in Chapter 20 and in experimental question E5, a gel retardation assay can be used to determine if a protein binds to DNA. This method can also determine if a protein binds to RNA. In the combinations described here, would you expect the migration of the RNA to be retarded due to the binding of a protein?
A. mRNA from a gene that is terminated in a p-independent manner plus p protein
B. mRNA from a gene that is terminated in a p-dependent manner plus p protein
C. Pre-mRNA from a protein-encoding gene that contains two introns plus the snRNP called U1
D. Mature mRNA from a protein-encoding gene that contains two introns plus the snRNP called U1