Consider a three-base sequence in the tem-plate of DNA: 5' . . . 123 . . . 3', in which 1, 2, and 3 refer to the relative positions of deoxyribonucleotides. Comment on the probable effect on the resulting protein if the following point mutations (one-base substitutions) occurred.
(a) Changing one purine for another in position 1
(b) Changing one pyrimidine for another in position 2
(c) Changing a purine to a pyrimidine in position 2
(d) Changing one purine for another in position 3