Draw a transition state diagram of (a) a nonenzymatic reaction and the corresponding enzyme-catalyzed reaction in which

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Draw a transition state diagram of (a) a nonenzymatic reaction and the corresponding enzyme-catalyzed reaction in which (b) S binds loosely to the enzyme and (c) S binds very tightly to the enzyme. Compare ∆G‡ for each case. Why is tight binding of S not advantageous?
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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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