Draw up coherence transfer pathways for the following experiments: (a) triple-quantum filtered COSY (which is identical to DQF COSY, except that p = ±3 between the last two pulses); (b) zero-quantum spectroscopy (which is identical to double-quantum spectroscopy, except that we have p = 0 during t1); (c) ZCOSY; (d) HSQC. In all cases, retain symmetrical pathways in t1.
For the HMQC experiment, draw up coherence transfer pathways which will give: (a) a P-type spectrum; (b) an N-type spectrum; (c) a spectrum which can be processed to give absorption mode lineshapes. Which of these spectra will be frequency discriminated in the co ω1 dimension?