Each of the following nucleophilic substitution reactions has been reported in the chemical literature. Many of them involve reactants that are somewhat more complex than those we have dealt with to this point. Nevertheless, you should be able to predict the product by analogy to what you know about nucleophilic substitution in simple systems.
(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)
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Transcribed Image Text:

Nal → Br:CH,COCH,CH,- 23acetone CH-CON acetic acid O,N NaCN CH,CH-OCH-CH-Br-Rural-water H,0, HO NC NaN CICH COCCH)s acetone water CH3 Nal acetono TsOCH, + CH,CH,Br- OCH3 CH,O CH,CH,CH-CHOH L. TsCl, pyridine 2. Lil, acetone CH30"