4S coronary mortality. The Scandinavian simvastatin survival study

(4S) was a randomized clinical trial designed to evaluate the effects of the cholesterol-lowering agent simvastatin in patients with coronary heart disease. Over 5.4 years of follow-up, the treatment group consisting of 2221 individuals experienced 111 fatal heart attacks. The placebo group of 2223 individuals experienced 189 such events.ff Calculate the risks in the groups and test the difference for significance. In relative terms, how much did simvastatin lower heart attack mortality?