A study for the development and validation of a sensitive and specific method for quantifying total activin-A

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A study for the development and validation of a sensitive and specific method for quantifying total activin-A concentrations has been reported on by Knight et al. (A-51). As part of the study they collected the following peripheral serum concentrations of activin-A in human subjects of differing reproductive status: normal follicular phase (FP), normal luteal phase (LP), pregnant

(PREG), ovarian hyperstimulated for in vivo fertilization (HYP), postmenopausal (PM), and normal adult males. Hint: Convert responses to logarithms before performing analysis.

FP LP PREG HYP PM Male 134.5 78.0 2674.0 253.1 793.1 196.7 159.2 130.4 945.6 294.3 385.1 190.6 133.2 128.3 5507.6 170.2 270.9 185.3 225.0 166.4 7796.5 219.8 640.3 335.4 146.4 115.2 5077.5 165.8 459.8 214.6 180.5 148.9 4541.9 159.0 Source: Data provided courtesy of Dr. Philip G. Knight.

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