Clinical Trial of Campral Campral (acamprosate) is a drug used to help patients continue their abstinence from the use of alcohol. Adverse reactions of Campral have been studied in clinical trials, and the table below summarizes results for digestive system effects among patients from different treatment groups (based on data from Forest Pharmaceuticals, Inc.). Use a 0.01 significance level to test the claim that experiencing an adverse reaction in the digestive system is independent of the treatment group. Does Campral treatment appear to have an effect on the digestive system?

Placebo Campral 1332 mg Campral 1998 mg Adverse Effect on Digestive System 344 89 8 No Effect on Digestive System 1362 774 71