In the article “Modulation of Cutaneous Aging With Calorie Restriction in Fischer 342 Rats” published in JAMA Facial Plastic Surgery (Bhattacharyya, et al., 2005), the authors reported the results of an experiment with a 3 × 2 factorial design for studying the factors age and diet on percentage elastic fibers. The ????-ratios for this experiment are given in Table 12.40. Use the information in Table 12.40 to answer the following questions.

(a) Based on the ????-ratios and their ????-values given in Table 12.40, which means should be separated?

(b) How many observations are used in computing each factor Age mean?

(c) How many observations are used in computing each factor Diet mean?

(d) How many observations are used in computing each Age×Diet treatment mean?

(e) Based on the result of part (a), determine the Bonferroni distance ???? for separating the interaction means when ???????????? = 1.13 and ???????? = 0.06.