Comparing cancer treatments. The progress of a type of cancer differs in women and men. A clinical experiment to compare four therapies for this cancer therefore treats sex as a blocking variable.

(a) You have 500 male and 300 female patients who are willing to serve as subjects. Use a diagram to outline a block design for this experiment. Figure 6.2 is a model.

(b) What are the advantages of a block design over a completely randomized design using these 800 subjects? What are the advantages of a block design over a completely randomized design using 800 male subjects?

AppendixLO1