Is honey a cough remedy? Pediatric researchers carried out a designed study to test whether a teaspoon of honey before bed calms a child’s cough and published their results in Archives of Pediatrics and Adolescent Medicine (Dec. 2007).

(This experiment was first described in Exercise 2.40, p. 79).

A sample of 105 children who were ill with an upper respiratory tract infection and their parents participated in the study. On the first night, the parents rated their children’s cough symptoms on a scale from 0 (no problems at all) to 6

(extremely severe) in five different areas. The total symptoms score (ranging from 0 to 30 points) was the variable of interest for the 105 patients. On the second night, the parents were instructed to give their sick child a dosage of liquid

“medicine” prior to bedtime. Unknown to the parents, some were given a dosage of dextromethorphan (DM)—an over-the-counter cough medicine—while others were given a similar dose of honey. Also, a third group of parents (the control group) gave their sick children no dosage at all.

Again, the parents rated their children’s cough symptoms, and the improvement in total cough symptoms score was determined for each child. The data (improvement scores)

for the study are shown in the next table. The goal of the researchers was to compare the mean improvement scores for the three treatment groups.

a. Identify the type of experimental design employed.

What are the treatments?

b. Conduct an analysis of variance on the data and interpret the results.

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Data for Exercise 10.41 Honey Dosage: 12 11 15 11 10 13 10 6 10 8 11 12 12 8 4 15 16 9 14 10 12 9 11 15 10 15 9 13 8 12 10 8 9 5 12 DM 4 6 9 4 7 7 7 9 12 10 11 6 3. Dosage: 49 12 7 6 8 12 12 4 12 13 7 10 13 9 4 4 10 15 9 No Dosage 5 8 6 10 8 12 8 7 7 167 (Control): 7 12 7 9 7 9 5 11 9 5 6 88 6 7 10 9 48 8 7 3 1 4 3