According to the Michaelis–Menten equation, when an enzyme is combined with a substrate of concentration s (in millimolars), the reaction rate (in micromolars/min) is

(a) Show, by computing that A is the limiting reaction rate as the concentration s approaches ∞.

(b) Show that the reaction rate R(s) attains one-half of the limiting value A when s = K.
(c) For a certain reaction, K = 1.25 mM and A = 0.1. For which concentration s is R(s) equal to 75% of its limiting value?

Transcribed Image Text:

R(s) = As K + S (A, K constants)