In the study of bioavailability in pharmacy, a drug is given to a patient. The level of concentration of the drug is then measured periodically, producing blood level curves such as the ones shown in the figure.
The areas under the curves give the total amount of the drug available to the patient for each milliliter of blood. In Exercises, use the trapezoidal rule with n = 10 to find the following areas.

Find the total area under the curve for Formulation A. What does this area represent?

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Average serum concentration (L/B) 7.0 6.0 5.0 4.0 3.0 2.0 1.0 0 Formulation A Formulation B Minimum effective concentration 5 10 15 Time after drug administration (hours) 20