When arterial blood enters a tissue capillary, it exchanges oxygen and carbon dioxide with its environment, as
Question:
When arterial blood enters a tissue capillary, it exchanges oxygen and carbon dioxide with its environment, as shown in this diagram.
The kinetics of this deoxygenation of hemoglobin in blood was studied with the aid of a tubular reactor by Nakamura and Staub (J. Physiol., 173, 161).
HbO2⇄k−1k1Hb+O2
Although this is a reversible reaction, measurements were made in the initial phases of the decomposition so that the reverse reaction could be neglected. Consider a system similar to the one used by Nakamura and Staub: the solution enters a tubular reactor (0.158 cm in diameter) that has oxygen electrodes placed at 5-cm intervals down the tube. The solution flow rate into the reactor is 19.6 cm3/s with CA0 = 2.33 × 10–6 mol/cm3. Electrode position
Percent decomposition of HbO2 0.00 1.93 3.82 5.68 7.48 9.25 11.00
a. Using the method of differential analysis of rate data, determine the reaction order and the forward specific reaction-rate constant k1 for the deoxygenation of hemoglobin.
b. Repeat using regression.
Step by Step Answer:
a b First we fit a polynomial to the data Using Po...View the full answer
