Confidence Interval for Bipolar Depression Treatment In clinical experiments involving different groups of independent samples, it is important that the groups be similar in the important ways that affect the experiment. In an experiment designed to test the effectiveness of paroxetine for treating bipolar depression, subjects were measured using the Hamilton depression scale with the results given below (based on data from “Double-Blind, Placebo-Controlled Comparison of Imipramine and Paroxetine in the Treatment of Bipolar Depression” by Nemeroff et al., American Journal of Psychiatry, Vol. 158, No. 6). Construct a 95% confidence interval for the difference between the two population means. Based on the results, does it appear that the two populations have different means? Should paroxetine be recommended as a treatment for bipolar depression?
Placebo group: n 5 43, 5 21.57, s 5 3.87 Paroxetine treatment group: n 5 33, 5 20.38, s 5 3.91