Provide a 95% CI for the incidence rate of neuroblastoma in the screened population. Express the 95% CI as (p₁, p₂), where p₁ and p₂ are in the units of number of cases per 100,000 children. Is p₀ (7.3 cases per 100,000 children) in this interval?

Cancer

A screening program for neuroblastoma (a type of cancer) was undertaken in Germany among children born between November 1, 1993, and June 30, 2000, who were 9 to 18 months of age between May 1995 and April 2000 [6].

A total of 1,475,773 children participated in the screening program, of whom 204 were diagnosed between 12 and 60 months of age. The researchers expected the incidence rate of neuroblastoma to be 7.3 per 100,000 children during this period in the absence of screening.