Provide a 95% CI for the mean difference in HgbA1c before minus the mean HgbA1c after use of the insulin pump?

Diabetes

The insulin pump is a device that delivers insulin to a diabetic patient at regular intervals. It presumably regulates insulin better than standard injections. However, data to establish this point are few, especially in children.

The following study was set up to assess the effect of use of the insulin pump on HgbA1c, which is a long-term marker of compliance with insulin protocols. In general, a normal range for HgbA1c is <7%.

Data were collected on 256 diabetic patients for 1 year before and after using the insulin pump. A subset of the data for 10 diabetic patients is given in Table 8.36.

Table 8.36 Mean HgbA1c 1 year before and 1 year after use of the insulin pump

 

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Mean HgbA1c 1 year before (96) Mean HgbA1c 1 year after (%) ID Before - After (%) 6.7 7.0 -0.3 7.4 7.4 3 9.2 8.6 0.6 4 9.6 8.1 1.5 7.4 6.8 0.6 6 8.1 7.0 1.1 7 10.8 8.5 2.3 7.1 7.7 -0.6 -1.8 7.9 9.7 10 10.8 7.7 3.1 Mean 8.5 7.9 0.65 0.9 sd 1.5 0.9 1.44