The article “The Effect of Enzyme Inducing Agents on the Survival Times of Rats Exposed to Lethal Levels of Nitrogen Dioxide” (Toxicology and Applied Pharmacology, 1978:

169–174) reports the following data on survival times for rats exposed to nitrogen dioxide (70 ppm) via different injection regimens. There were rats in each group.

Regimen si 1.

Control 166 322.

3-Methylcholanthrene 303 533.

Allylisopropylacetamide 266 544.

Phenobarbital 212 355.

Chlorpromazine 202 346.

p-Aminobenzoic Acid 184 31

a. Test the null hypothesis that true average survival time does not depend on an injection regimen against the alternative that there is some dependence on an injection regimen using .

b. Suppose that CIs for k different parametric functions are computed from the same ANOVA data set. Then it is easily verified that the simultaneous confidence level is at least . Compute CIs with a simultaneous confidence level of at least 98% for and m4 1 m5) 2 m6 1 4 m1 2 (m2 1 m3 1 1 5 (m2 1 m3 1 m4 1 m