The enzyme hexokinase adds a phosphate to D-glucose but ignores its mirror image, L-glucose. Suppose that you

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The enzyme hexokinase adds a phosphate to D-glucose but ignores its mirror image, L-glucose. Suppose that you were able to synthesize hexokinase entirely from D amino acids, which are the mirror image of the normal L-amino acids.

A. Assuming that the “D” enzyme would fold to a stable conformation, what relationship would you expect it to bear to the normal “L” enzyme?

B. Do you suppose the “D” enzyme would add a phosphate to L-glucose, and ignore D-glucose?

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Molecular Biology Of The Cell

ISBN: 9780815344322

6th Edition

Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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