The following reaction sequence was used by E J Corey (J Am Chem Soc 1969, 91, 56755677) at the beginning of a synthesis of prostaglandin F 2 and prostaglandin E 2 Explain what is involved in this reaction and why it is a reasonable process (1) strong base (2) CI OCH 3 LOCH 3

Question: The following reaction sequence was used by E. J. Corey (J. Am. Chem. Soc. 1969, 91, 56755677) at the beginning of a synthesis of prostaglandin

The following reaction sequence was used by E. J. Corey (J. Am. Chem. Soc. 1969, 91, 5675–5677) at the beginning of a synthesis of prostaglandin F_2αand prostaglandin E₂. Explain what is involved in this reaction and why it is a reasonable process. (1) strong base (2) CI OCH 3 LOCH 3

(1) strong base (2) CI OCH 3 LOCH 3

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