On the package insert for the drug labetalol, used in the control of blood pressure and hypertension,

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On the package insert for the drug labetalol, used in the control of blood pressure and hypertension, is given the following structure:OH T -CHCHCHNHCHCH- T CH3 labetalol hydrochloride CNH, -OH HCI

(a) Labetalol is claimed to be a salt. Explain by giving a more detailed structure.

(b) What happens to labetalol?HCl when it is treated with one equivalent of NaOH at room temperature?

(c) What happens to labetalol when it is treated with an excess of aqueous NaOH and heat?

(d) What are the products formed when labetalol is treated with 6 M aqueous HCl and heat?

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Organic Chemistry

ISBN: 9781936221349

6th Edition

Authors: Marc Loudon, Jim Parise

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