The scientists who developed Norvir stated that one of the significant interactions of the inhibitor with the

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The scientists who developed Norvir stated that one of the significant interactions of the inhibitor with the enzyme is hydrogen bonding of a thiazole nitrogen (the thiazole on the right side of the structure on p. 1438) with a backbone N¬H of a nearby peptide bond on the enzyme. Draw a thiazole such as the one in Norvir and, using it, show such a hydrogen-bonding interaction.

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Organic Chemistry

ISBN: 9781936221349

6th Edition

Authors: Marc Loudon, Jim Parise

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