In Problem 7.4, we saw that an intramolecular substitution reaction can occur when the nucleophilic center and electrophilic center are present in the same compound. Draw the transition state of the reaction in Problem 7.4.

When a nucleophile and electrophile are tethered to each other (that is, both present in the same compound), an intramolecular substitution reaction can occur, as shown. Assume that this reaction occurs via a concerted process and draw the mechanism.

Transcribed Image Text:

Br BrO