Meclizine, shown below, is an antiemetic (prevents nausea and vomiting). a) Would you expect meclizine to be

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Meclizine, shown below, is an antiemetic (prevents nausea and vomiting).

a) Would you expect meclizine to be an antihistamine as well? Justify your answer.

b) This drug is known to cause sedation. Describe the source of the sedative properties of meclizine.

c) Can you suggest a structural modification that could possibly modify the sedative properties of meclizine?

CI N. N. Meclizine

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Organic Chemistry

ISBN: 978-0470917800

1st edition

Authors: David R. Klein

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