1. (16pts) You are trying to dose a drug that follows one-compartment pharmacokinetics, with a t1/2 of 7hrs, and apparent volume of distribution of 30 L.

Instead of bolus i.v., the doctor decides to set up a drip i.v. line into the patient. At what rate (mg/hr) should the doctor set the i.v. drip so as to attain a steadystate concentration of 20 mg/L?